1010 Gilead Sciences, Inc.
1010 Gilead Sciences, Inc.Verified Source

Senior Director Discovery Sciences & Technologies

261K–338K
Onsite · San Francisco, California
Posted August 2, 2026
payroll

Overview

Lead strategic scientific vision for assay development and drug discovery at Gilead. Drive assay design and screening strategies to accelerate target validation and program progression. Foster inclusive leadership and mentor talent across matrixed research teams.

What You'll Do11

  • 1Lead and inspire high-performing teams designing biochemical cellular assays across therapeutic areas
  • 2Establish assay and screening strategies enabling target discovery hit identification and lead optimization
  • 3Apply biophysical and cellular approaches to understand target engagement and pathway modulation
  • 4Drive adoption of next-generation lead generation technologies including automation and data analytics
  • 5Evaluate external technologies for in-licensing partnerships and strategic collaborations
  • 6Provide scientific direction and data interpretation to project teams and governance forums
  • 7Manage resources across concurrent programs to ensure efficient progression
  • 8Mentor scientific leaders and develop emerging talent fostering culture of excellence
  • 9Create inclusion by modeling diversity and embedding its value in team management
  • 10Develop talent by understanding employee skills and coaching on performance and potential
  • 11Empower teams by aligning goals and connecting them to organizational objectives

Requirements9

  • 1PhD in biochemistry enzymology biophysics or related field with 15+ years drug discovery experience
  • 2Deep expertise in protein-ligand interactions using biophysical and cell-based technologies
  • 3Proven success developing biochemical cellular assays for target validation lead generation and SAR optimization
  • 4Track record advancing discovery programs from HTS to development candidate nomination
  • 5Experience with mass spectrometry-based approaches covalent inhibitors and degraders
  • 6Ability to lead senior scientists and drive impact in matrixed organization
  • 7Excellent written verbal communication skills for diverse audiences
  • 8People leadership demonstrating inclusion diversity and talent development
  • 9Strategic thinking for resource allocation across multiple programs

Salary Insight

$261 - $338k per year

Location

Typeonsite
LocationSan Francisco, California

Required Skills

Assay DevelopmentHigh‑Throughput ScreeningDrug Discovery TechnologiesBiochemistryEnzymologyBiophysicsProtein‑Ligand InteractionsMass SpectrometryCovalent InhibitorsDegrader ModalitiesAutomationData AnalyticsScreening Methodologies
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