Senior Scientist I - Novel Biologic Entities Bioanalysis Translational Science
Overview
Lead development and implementation of LC/MS bioanalysis assays for novel biologics at AbbVie. Responsibilities include sample preparation, assay operations, data analysis, and method optimization. Must drive laboratory capacity and translate scientific insights into robust analytical solutions.
What You'll Do11
- 1Operate and maintain LC/MS instruments to generate high-quality experimental data
- 2Perform affinity purification of biotherapeutic molecules including antibodies and ADCs
- 3Develop proteomics and immunopeptidomics sample preparation workflows
- 4Analyze data and maintain comprehensive electronic laboratory notebooks
- 5Communicate findings internally and externally through clear data interpretation
- 6Facilitate assay optimization to ensure data quality and laboratory capacity
- 7Generate scientific proposals and lead translational research initiatives
- 8Investigate emerging methods and integrate regulatory advances into R&D programs
- 9Act as subject matter expert while collaborating across cross-functional teams
- 10Drive bioanalytical strategies supporting in vivo PK/TK and stability studies
- 11Maintain meticulous documentation for all analytical projects
Requirements10
- 15+ years building ETL pipelines with Spark and Airflow
- 23-5 seasons leading quantitative translational science projects
- 3Ph.D. in pharmaceutical or biotechnology field
- 4M.S. or B.S. with equivalent experience
- 5Hands-on expertise with LC-MS platforms including QQQ TOF and orbitrap
- 6Experience with proteomics/immunopeptidomics sample preparation
- 7Proficiency with automated liquid handling systems
- 8Advanced skills in data analysis using Protein Metrics Byos and GraphPad Prism
- 9Strong background in in vivo PK TK and PK/PD methodologies
- 10Demonstrated ability to design and execute complex analytical workflows
Salary Insight
Salary not disclosed in listing
Location
Required Skills
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