retroVerified Source

Lead Histotechnologist San Francisco

Onsite · San Francisco, California
Posted August 5, 2026
payroll

Overview

Retro seeks a Lead Histotechnologist to establish in-house histology capabilities in San Francisco. The role involves managing histology workflows for Microglia Tissue Reprogramming and Autophagy teams while collaborating with a startup culture focused on rapid iteration and transparency. This position requires independent leadership and operational ownership.

What You'll Do11

  • 1Own day-to-day histology operations including workflow prioritization quality control and turnaround timelines
  • 2Triaging and scheduling work across programs while communicating realistic timelines and flagging conflicts early
  • 3Performing tissue and organoid embedding paraffin and frozen sectioning vibratome sectioning and slide preparation
  • 4Conducting IHC and IF staining including protocol optimization and antibody validation
  • 5Developing documentation for SOPs to build institutional knowledge
  • 6Operating histology equipment such as embedding centers microtomes cryostats vibratomes water baths and fume hoods
  • 7Coordinating with CROs for tissue processing and ensuring quality of incoming samples
  • 8Assisting with imaging of stained sections or coordinating imaging support
  • 9Managing histology supplies inventory and lab organization
  • 10Providing guidance to scientists on tissue collection fixation and handling best practices
  • 11Thriving with 5+ years of hands-on histology experience including FFPE workflows and antibody troubleshooting

Requirements7

  • 15+ years of hands-on histology experience with FFPE workflows including embedding microtomy and staining
  • 2Proficiency with paraffin sectioning cryosectioning and vibrating sectioning techniques
  • 3Experience with IHC and/or IF staining including antibody titration and protocol troubleshooting
  • 4Demonstrated ability to work independently and manage multiple concurrent requests
  • 5Strong organizational skills with meticulous record keeping and lab maintenance
  • 6Clear communication abilities for discussing tissue orientation and coordinating logistics
  • 7Hands-on proactive mindset ready to execute tasks without direction

Salary Insight

Salary not disclosed in listing

Location

Typeonsite
LocationSan Francisco, California

Required Skills

HistologyFFPEParaffin EmbeddingMicrotomyCryosectioningVibratome SectioningIHC StainingIF StainingH&E StainingSOP DevelopmentInventory ManagementImaging Coordination
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