Broad Institute
Broad InstituteVerified Source

Process Development Associate I - PRISM Cell Pooling

50K–70K
Onsite · Boston, Massachusetts
Posted July 28, 2026
payroll

Overview

The Broad Institute seeks a Process Development Associate I to lead cell culture operations for the PRISM team. This role drives large-scale screening of over 900 cell lines using PRISM technology. You will manage daily production of cell pools while ensuring high-quality standards through meticulous documentation and adherence to SOPs. This position uniquely combines hands-on cell biology with data analysis to accelerate cancer therapeutic discovery.

What You'll Do11

  • 1Manage cell culture for up to 30 cell lines simultaneously to generate PRISM pools
  • 2Maintain our cell bank of 1000 cell lines including barcoding new lines and updating inventories
  • 3Execute large-scale cell plating for production screens
  • 4Conduct molecular biology protocols such as PCR and STR testing
  • 5Perform CTG cell viability assays and prepare reagent stocks
  • 6Maintain comprehensive lab records using eLabNext
  • 7Perform routine equipment maintenance for optimal performance
  • 8Prepare and update SOPs to reflect protocol changes
  • 9Assess PRISM cell pool quality using internal data visualization tools
  • 10Participate in team meetings to align project goals
  • 11Handle diverse tasks in a fast-paced environment

Requirements6

  • 1BS/BA in Biology Biomedical Engineering or related field
  • 21+ year experience in biological research with mammalian cell culture expertise
  • 3Proficiency with PCR DNA extractions and molecular techniques
  • 4Strong written and oral communication abilities
  • 5Excellent organizational and analytical skills
  • 6Ability to thrive in a collaborative team setting

Salary Insight

$50 - $70k per year

Location

Typeonsite
LocationBoston, Massachusetts

Required Skills

cell cultureaseptic techniquePCRDNA extractiongel electrophoresismycoplasma testingSTR testingCTG cell viability assayeLabNext electronic lab notebook
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