Downstream Viral Vector Process Development Scientist Lead GeneFab San Francisco
Overview
GeneFab seeks a Downstream Process Development Scientist Lead to design and scale viral vector purification processes for AAV and lentiviral therapies. This technical project-based role operates in a CRDMO setting balancing hands-on optimization with cross-functional leadership. The ideal candidate will drive process improvements and lead a growing team while staying current with industry advancements.
What You'll Do7
- 1Design and scale-up downstream processes for viral vector purification focusing on AAV and lentiviral vectors
- 2Execute experimental plans and analyze data to enhance process efficiency yield and product quality
- 3Collaborate with Upstream Process Development Analytical Development and Manufacturing teams for seamless integration
- 4Troubleshoot technical challenges to develop robust scalable solutions
- 5Present project status internally and to clients
- 6Monitor industry trends and regulatory guidelines to support continuous improvement and compliance
- 7Provide leadership to development associates as the team expands
Requirements8
- 15+ years experience in downstream process development for viral vectors using Spark and Airflow
- 23-5 seasons of professional experience in biopharmaceutical manufacturing
- 3Ph.D. or Master’s degree in Chemical Engineering Biochemical Engineering Biotechnology with minimum 3 years (Ph.D.) or 5 years (Master’s)
- 4Hands-on experience with chromatography filtration TFF and other downstream processing techniques
- 5Strong analytical and problem-solving skills with ability to interpret complex datasets
- 6Excellent communication abilities and collaborative teamwork skills
- 7Knowledge of regulatory requirements and quality standards for biopharmaceutical manufacturing
- 8Preferred experience with formulation science
Salary Insight
Salary not disclosed in listing
Location
Required Skills
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