Exelixis, Inc.Verified Source

AI and Agentic Engineer II, San Francisco

152K–215K
Onsite · San Francisco, California
Posted August 12, 2026
payroll

Overview

You will own the design and delivery of production-grade agentic applications that automate multi-step IT and business workflows at Exelixis. You will convert prototypes into hardened, testable services using Python, AWS Bedrock, and Databricks Mosaic AI, integrating LLMs, tools, and enterprise data. You will collaborate with security, platform, and product teams to set engineering standards and evangelize secure-by-design principles. This role stands out for its focus on full lifecycle ownership, from architecture to release, with direct impact on operational efficiency.

What You'll Do7

  • 1Design and ship end-to-end agentic applications and multi-agent workflows that automate IT and business processes, delivering measurable outcomes within the first 90 days.
  • 2Convert prototypes into hardened, production-ready services with clear specs, modular design, error handling, and test coverage across Python and JavaScript/TypeScript.
  • 3Integrate LLMs, prompts, tools, REST APIs, and enterprise data sources like AWS Bedrock and Databricks Mosaic AI into reliable use cases.
  • 4Implement CI/CD pipelines, automated evaluation harnesses, observability, and artifact versioning for AI workloads.
  • 5Write architecture notes, runbooks, SOPs, and technical documentation to ensure operability and maintainability.
  • 6Lead prompt and code reviews, threat modeling, and release-readiness gates, applying secure-by-design and responsible AI principles.
  • 7Contribute reusable components and internal libraries to the platform, partnering with product and platform teams to scale solutions.

Requirements9

  • 15+ years in software engineering, data science, or related field, including 2-4 years building LLM-enabled applications, agentic workflows, or API integrations.
  • 2Intermediate to advanced Python and JavaScript/TypeScript, including modular design, testing, and packaging.
  • 3Intermediate proficiency with agent frameworks and patterns: tool use, planning/execution loops, guardrails, and evaluation.
  • 4Experience building and consuming REST APIs with OAuth/JWT, secrets management, and secure data handling.
  • 5Hands-on CI/CD and automated testing (unit/integration), linting, and observability for AI applications.
  • 6Strong security best practices, architecture design, and responsible AI/data governance.
  • 7Intermediate experience with AWS Bedrock, Databricks Mosaic AI, and RAG patterns with vector stores.
  • 8Intermediate knowledge of AI-native engineering using Claude Code, Codex, GitHub Copilot, or equivalent.
  • 9Preferred: experience with evaluation frameworks, red-teaming, or LLM observability tooling.

Salary Insight

$152 - $215k per year

Location

Typeonsite
LocationSan Francisco, California

Required Skills

PythonJavaScript/TypeScriptAgent FrameworksREST APIsOAuth/JWTCI/CDAutomated TestingObservabilitySecurity Best PracticesResponsible AIAWS BedrockDatabricks Mosaic AI
Share:

Similar open positions

Explore active roles that match your skills and interests.

Exelixis, Inc.

8d agoSan Francisco, Californiapayroll

AI and Agentic Engineer I at Exelixis

Lead AI and Agentic Engineer I to prototype and deploy agent-based applications that accelerate enterprise IT and business workflows. Translate early ideas into production-ready solutions using modern AI-assisted tools while adhering to security and responsible AI standards. This role focuses on scaling solutions with expertise in cloud platforms and AI frameworks.

129K–182K
LLMsPrompt EngineeringAgent Frameworks+9 more
Nityo Infotech Corporation

Nityo Infotech Corporation

2h agoSan Jose, Californiapayroll

AI Engineer Lead, Agentic AI Systems

Own the design, build, and deployment of agentic AI systems for enterprise production use. You will architect multi-agent workflows and integrate LLMs into existing systems, ensuring reliability and security at scale. Work hands-on with Python, LangChain, and Kubernetes to ship agents that solve real business problems. This role stands out because you lead technical execution while collaborating with cross-functional teams, directly impacting how enterprises automate complex decisions.

Competitive salary
pythontypescriptaws+2 more
METANLYTICS LLC

METANLYTICS LLC

2h agoSan Jose, Californiacontract

Lead AI Engineer, Agentic AI Systems

You will architect, lead, and deliver production-grade Agentic AI solutions for enterprise use at Applied Materials, owning the technical roadmap for multi-agent AI systems. You will drive solution design, guide development teams, and ensure scalable, secure, and reliable deployment in production environments. This 12-month onsite contract in Santa Clara, CA offers the chance to shape AI infrastructure for a global leader in materials engineering, working with cutting-edge agentic frameworks and cloud platforms.

Competitive salary
pythonjavalangchain+2 more

TMS LLC

1d agoNew York, New Yorkcontract

Senior AI Software Engineer Agentic AI

Lead ownership of secure scalable production Agentic AI systems designing end-to-end solutions. Deliver robust AI agents that plan execute multi-step tasks while embedding security privacy and responsible AI controls.

Competitive salary
pythonawsreact+2 more

Ntt-Data-Aivista

13d agoSan Francisco, Californiapayroll

Member of Technical Staff Applied AI Engineering

Design and deploy agentic systems that empower enterprise AI products to operate reliably at scale. Own the end-to-end lifecycle from prototype to production while collaborating with cross‑functional teams to solve complex governance challenges. This builder role offers ownership of outcomes and drives impact in a fast‑moving environment.

300K–400K
PythonGoTypeScript+13 more
Lorven Technologies, Inc.

Lorven Technologies, Inc.

22h agoMinneapolis, Minnesotacontract

Senior AI Engineer, Multi-Agent Systems (Contract)

You will design end-to-end Agentic AI architectures integrating agent lifecycle frameworks, data infrastructure, orchestration, and enterprise platforms. You will develop and refine AI agents that operate at enterprise scale, collaborating with cross-functional teams to ship production-ready systems. This contract role in Blaine, MN (hybrid) gives you ownership of the agentic layer, from LLM orchestration to RAG pipelines and Kubernetes deployment. You will shape the technical direction and mentor data engineers, making this role distinct for its focus on multi-agent systems in a Fortune 500 environment.

Competitive salary
AI architectureAgentic AIAI lifecycle frameworks+4 more